IUBMB Enzyme Nomenclature


Accepted name: xylono-1,5-lactonase

Reaction: D-xylono-1,5-lactone + H2O = D-xylonate

Other name(s): xylC (gene name); D-xylono-1,5-lactone lactonase

Systematic name: D-xylono-1,5-lactone lactonohydrolase

Comments: The enzyme, found in bacteria, participates in the degradation of D-xylose. cf. EC, xylono-1,4-lactonase.


1. Toivari, M., Nygard, Y., Kumpula, E.P., Vehkomaki, M.L., Bencina, M., Valkonen, M., Maaheimo, H., Andberg, M., Koivula, A., Ruohonen, L., Penttila, M. and Wiebe, M.G. Metabolic engineering of Saccharomyces cerevisiae for bioconversion of D-xylose to D-xylonate. Metab. Eng. 14 (2012) 427-436. [PMID: 22709678]

2. Nygard, Y., Maaheimo, H., Mojzita, D., Toivari, M., Wiebe, M., Resnekov, O., Gustavo Pesce, C., Ruohonen, L. and Penttila, M. Single cell and in vivo analyses elucidate the effect of xylC lactonase during production of D-xylonate in Saccharomyces cerevisiae. Metab. Eng. 25 (2014) 238-247. [PMID: 25073011]

[EC created 2019]

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