IUBMB Enzyme Nomenclature


Accepted name: isoamyl acetate esterase

Reaction: 3-methylbutyl acetate + H2O = 3-methylbutanol + acetate

Other name(s): IAH1 (gene name)

Systematic name: 3-methylbutyl acetate acetohydrolase

Comments: The enzyme, characterized from the yeast Saccharomyces cerevisiae, hydrolyses acetate esters. It acts preferentially on 3-methylbutyl acetate, a major determinant of sake flavor.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number:


1. Fukuda, K., Kiyokawa, Y., Yanagiuchi, T., Wakai, Y., Kitamoto, K., Inoue, Y. and Kimura, A. Purification and characterization of isoamyl acetate-hydrolyzing esterase encoded by the IAH1 gene of Saccharomyces cerevisiae from a recombinant Escherichia coli. Appl. Microbiol. Biotechnol. 53 (2000) 596-600. [PMID: 10855721]

[EC created 2019]

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