Reaction: D-glucono-1,5-lactone + H2O = D-gluconate
For diagram click here.
Other name(s): lactonase; aldonolactonase; glucono-δ-lactonase; gulonolactonase
Systematic name: D-glucono-1,5-lactone lactonohydrolase
Comments: Acts on a wide range of hexose-1,5-lactones. The hydrolysis of L-gulono-1,5-lactone was previously listed as EC 22.214.171.124, aldonolactonase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9012-73-1
1. Brodie, A.F. and Lipmann, F. Identification of a gluconolactonase. J. Biol. Chem. 212 (1955) 677-685.
2. Bublitz, C. and Lehninger, A.L. The role of aldonolactonase in the conversion of L-gulonate to L-ascorbate. Biochim. Biophys. Acta 47 (1961) 288-297.
3. Suzuki, K., Kawada, M. and Shimazono, N. Soluble lactonase. Identity of lactonase I and aldonolactonase with gluconolactonase. J. Biochem. (Tokyo) 49 (1961) 448-449.