IUBMB Enzyme Nomenclature


Accepted name: acylcarnitine hydrolase

Reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine

Other name(s): high activity acylcarnitine hydrolase; HACH; carnitine ester hydrolase; palmitoylcarnitine hydrolase; palmitoyl-L-carnitine hydrolase; long-chain acyl-L-carnitine hydrolase; palmitoyl carnitine hydrolase

Systematic name: O-acylcarnitine acylhydrolase

Comments: Acts on higher fatty acid (C6 to C18) esters of L-carnitine; highest activity is with O-decanoyl-L-carnitine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37278-42-5


1. Mahadevan, S. and Sauer, F. Carnitine ester hydrolase of rat liver. J. Biol. Chem. 244 (1969) 4448-4453. [PMID: 5806585]

2. Mentlein, R., Reuter, G. and Heymann, E. Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function. Arch. Biochem. Biophys. 240 (1985) 801-810. [PMID: 4026306]

[EC created 1972]

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