IUBMB Enzyme Nomenclature


Accepted name: triacylglycerol lipase

Reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate

Other name(s): lipase; triglyceride lipase; tributyrase; butyrinase; glycerol ester hydrolase; tributyrinase; Tween hydrolase; steapsin; triacetinase; tributyrin esterase; Tweenase; amno N-AP; Takedo 1969-4-9; Meito MY 30; Tweenesterase; GA 56; capalase L; triglyceride hydrolase; triolein hydrolase; tween-hydrolyzing esterase; amano CE; cacordase; triglyceridase; triacylglycerol ester hydrolase; amano P; amano AP; PPL; glycerol-ester hydrolase; GEH; meito Sangyo OF lipase; hepatic lipase; lipazin; post-heparin plasma protamine-resistant lipase; salt-resistant post-heparin lipase; heparin releasable hepatic lipase; amano CES; amano B; tributyrase; triglyceride lipase; liver lipase; hepatic monoacylglycerol acyltransferase

Systematic name: triacylglycerol acylhydrolase

Comments: The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolysed.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9001-62-1


1. Korn, E.D. and Quigley, T.W. Lipoprotein lipase of chicken adipose tissue. J. Biol. Chem. 226 (1957) 833-839.

2. Lynn, W.S. and Perryman, N.C. Properties and purification of adipose tissue lipase. J. Biol. Chem. 235 (1960) 1912-1916.

3. Sarda, L. and Desnuelle, P. Action de la lipase pancréatique sur les esters en émulsion. Biochim. Biophys. Acta 30 (1958) 513-521.

4. Singer, T.P. and Hofstee, B.H.J. Studies on wheat germ lipase. I. Methods of estimation, purification and general properties of the enzyme. Arch. Biochem. 18 (1948) 229-243.

5. Singer, T.P. and Hofstee, B.H.J. Studies on wheat germ lipase. II. Kinetics. Arch. Biochem. 18 (1948) 245-259.

[EC created 1961]

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