IUBMB Enzyme Nomenclature


Accepted name: fatty-acyl-ethyl-ester synthase

Reaction: A long-chain-fatty-acyl ethyl ester + H2O = a long-chain-fatty acid + ethanol

Other name(s): FAEES

Systematic name: long-chain-fatty-acyl-ethyl-ester acylhydrolase

Comments: In the reverse reaction, forms ethyl esters from fatty acids and ethanol in the absence of coenzyme A or ATP. Best substrates are unsaturated octadecanoic acids; palmitate, stearate and arachidonate also act, but more slowly.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 90119-16-7


1. Mogelson, S. and Lange, L.G. Nonoxidative ethanol metabolism in rabbit myocardium: purification to homogeneity of fatty acyl ethyl ester synthase. Biochemistry 23 (1984) 4075-4081. [PMID: 6487591]

[EC created 1989]

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