Reaction: 3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid
Comments: This is a secondary reaction to the RNA 5'-end directed cleavage 13-19 nucleotides from the RNA end performed by EC 3.1.26.13 (retroviral ribonuclease H).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:
References:
1. Schatz, O., Mous, J. and Le Grice, S.F. HIV-1 RT-associated ribonuclease H displays both endonuclease and 3'—5' exonuclease activity. EMBO J. 9 (1990) 1171-1176. [PMID: 1691093]