IUBMB Enzyme Nomenclature


Accepted name: oligonucleotidase

Reaction: Exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates

Other name(s): oligoribonuclease

Comments: Also hydrolyses NAD+ to NMN and AMP. Formerly EC

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37288-23-6


1. Futai, M. and Mizuno, D. A new phosphodiesterase forming nucleoside 5'-monophosphate from rat liver. Its partial purification and substrate specificity for nicotinamide adenine dinucleotide and oligonucleotides. J. Biol. Chem. 242 (1967) 5301-5307. [PMID: 4294333]

[EC created 1972 as EC, transferred 1978 to EC]

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