IUBMB Enzyme Nomenclature

EC 3.1.16.1

Accepted name: spleen exonuclease

Reaction: Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates

Other name(s): 3'-exonuclease; spleen phosphodiesterase; 3'-nucleotide phosphodiesterase; phosphodiesterase II

Comments: Preference for single-stranded substrate. Formerly EC 3.1.4.18 (cf. EC 3.1.31.1 micrococcal nuclease).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9068-54-6

References:

1. Bernardi, A. and Bernardi, G. Spleen acid nuclease, in Boyer, P.D. (Ed.), The Enzymes, 3rd edn., vol. 4, Academic Press, New York, 1971, pp. 329-336.

[EC 3.1.16.1 created 1972 as EC 3.1.4.18, transferred 1978 to EC 3.1.16.1]


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