IUBMB Enzyme Nomenclature


Accepted name: spleen exonuclease

Reaction: Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 3'-phosphates

Other name(s): 3'-exonuclease; spleen phosphodiesterase; 3'-nucleotide phosphodiesterase; phosphodiesterase II

Comments: Preference for single-stranded substrate. Formerly EC (cf. EC micrococcal nuclease).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9068-54-6


1. Bernardi, A. and Bernardi, G. Spleen acid nuclease, in Boyer, P.D. (Ed.), The Enzymes, 3rd edn., vol. 4, Academic Press, New York, 1971, pp. 329-336.

[EC created 1972 as EC, transferred 1978 to EC]

Return to EC 3.1.16 home page
Return to EC 3.1 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page