IUBMB Enzyme Nomenclature


Accepted name: acetoacetyl-CoA hydrolase

Reaction: acetoacetyl-CoA + H2O = CoA + acetoacetate

For diagram click here.

Other name(s): acetoacetyl coenzyme A hydrolase; acetoacetyl CoA deacylase; acetoacetyl coenzyme A deacylase

Systematic name: acetoacetyl-CoA hydrolase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37288-10-1


1. Aragón, J.J. and Lowenstein, J.M. A survey of enzymes which generate or use acetoacetyl thioesters in rat liver. J. Biol. Chem. 258 (1983) 4725-4733. [PMID: 6131897]

2. Drummond, G.I. and Stern, J.R. Enzymes of ketone body metabolism. II. Properties of an acetoacetate-synthesizing enzyme prepared from ox liver. J. Biol. Chem. 235 (1960) 318-325.

[EC created 1972]

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