Reaction: betaine-CoA + H2O = glycine betaine + CoA
Glossary: betaine-CoA = glycinebetainyl-CoA = betainyl-CoA = N,N,N-trimethylglycyl-CoA
Other name(s): cdhB (gene name)
Systematic name: betaine-CoA hydrolase
Comments: The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in an L-carnitine degradation pathway.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Wargo, M.J. and Hogan, D.A. Identification of genes required for Pseudomonas aeruginosa carnitine catabolism. Microbiology (Reading) 155 (2009) 2411-2419. [PMID: 19406895]
2. Bastard, K., Smith, A.A., Vergne-Vaxelaire, C., Perret, A., Zaparucha, A., De Melo-Minardi, R., Mariage, A., Boutard, M., Debard, A., Lechaplais, C., Pelle, C., Pellouin, V., Perchat, N., Petit, J.L., Kreimeyer, A., Medigue, C., Weissenbach, J., Artiguenave, F., De Berardinis, V., Vallenet, D. and Salanoubat, M. Revealing the hidden functional diversity of an enzyme family. Nat. Chem. Biol. 10 (2014) 42-49. [PMID: 24240508]