Reaction: (3R)-atrochrysone-2-carbonyl-[acyl-carrier protein] + H2O = (3R)-atrochrysone-2-carboxylate + [acyl-carrier protein]
Glossary: (3R)-atrochrysone-2-carboxylate = (3R)-3,6,8,9-tetrahydroxy-3-methyl-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxylate
Other name(s): TpcB; ACTE; atrochrysone carboxylate thioesterase
Systematic name: atrochrysone-2-carbonyl-[acyl-carrier protein] hydrolase
Comments: The enzyme was isolated from the mould Aspergillus fumigatus. It is a metallo-β-lactamase type thioesterase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Throckmorton, K., Lim, F.Y., Kontoyiannis, D.P., Zheng, W. and Keller, N.P. Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus, Environ. Microbiol. 18 (2016) 246-259. [PMID: 26242966]