IUBMB Enzyme Nomenclature

EC 3.1.22.1

Accepted name: deoxyribonuclease II

Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products

Other name(s): DNase II; pancreatic DNase II; deoxyribonucleate 3'-nucleotidohydrolase; DNase II; pancreatic DNase II; acid deoxyribonuclease; acid DNase

Comments: Preference for double-stranded DNA. Formerly EC 3.1.4.6.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9025-64-3

References:

1. Bernardi, G. Spleen acid deoxyribonuclease, in Cantoni, G.L. and Davies, D.R. (Eds.), Procedures in Nucleic Acid Research, Harper and Row, New York, 1966, pp. 102-121.

[EC 3.1.22.1 created 1961 as EC 3.1.4.6, transferred 1978 to EC 3.1.22.1, modified 1981]


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