IUBMB Enzyme Nomenclature


Accepted name: deoxyribonuclease X

Reaction: Endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes

Other name(s): Escherichia coli endodeoxyribonuclease; Escherichia coli endodeoxyribonuclease X

Comments: Preference for supercoiled DNA; little activity on linear double-stranded DNA. Inhibited by single-stranded DNA, ATP and AMP.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 97002-82-9


1. Ghosh, S. and DasGupta, U. Studies with endonuclease X: a new deoxyendonuclease of E. coli that preferentially cleaves supercoiled plasmid DNA. Curr. Trends Life Sci. 12 (1984) 79-88.

[EC created 1992]

Return to EC 3.1.22 home page
Return to EC 3.1 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page