IUBMB Enzyme Nomenclature


Accepted name: ribonuclease IV

Reaction: Endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups

Other name(s): endoribonuclease IV; poly(A)-specific ribonuclease

Comments: Forms oligonucleotides with an average chain length of 10.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 61536-76-3


1. Müller, E.G. Endoribonuclease IV. A poly(A)-specific ribonuclease from chick oviduct. 1. Purification of the enzyme. Eur. J. Biochem. 70 (1976) 241-248. [PMID: 1009928]

2. Müller, E.G., Seibert, G., Steffen, R. and Zahn, R.K. Endoribonuclease IV. 2. Further investigation on the specificity. Eur. J. Biochem. 70 (1976) 249-258. [PMID: 1009929]

[EC created 1984]

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