IUBMB Enzyme Nomenclature


Accepted name: ribonuclease M5

Reaction: Endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor

Other name(s): RNase M5; 5S ribosomal maturation nuclease; 5S ribosomal RNA maturation endonuclease

Comments: Converts the 5S-rRNA precursor from Bacillus subtilis into 5S-rRNA, with 5'-phosphate and 3'-hydroxy groups.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 62253-00-3


1. Sogin, M.L., Pace, B. and Pace, N.R. Partial purification and properties of a ribosomal RNA maturation endonuclease from Bacillus subtilis. J. Biol. Chem. 252 (1977) 1350-1357. [PMID: 402365]

[EC created 1986]

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