IUBMB Enzyme Nomenclature


Accepted name: ribonuclease [poly-(U)-specific]

Reaction: Endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups

Other name(s): ribonuclease (uracil-specific); uracil-specific endoribonuclease; uracil-specific RNase

Comments: Forms oligonucleotides with chain lengths of 6 to 12.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 54249-90-0


1. Bachmann, M., Trautmann, F., Messer, R., Zahn, R.K., Meyer zum Büschenfelde, K.H. and Müller, W.E.G. Association of a polyuridylate-specific endoribonuclease with small nuclear ribonucleo-proteins which had been isolated by affinity chromatography using antibodies from a patient with systemic lupus erythematosus. Eur. J. Biochem. 136 (1983) 447-451. [PMID: 6227485]

[EC created 1986]

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