IUBMB Enzyme Nomenclature


Accepted name: validoxylamine A 7'-phosphate phosphatase

Reaction: validoxylamine A 7'-phosphate + H2O = validoxylamine A + phosphate

For diagram of reaction click here.

Glossary: validoxylamine A = (1S,2S,3R,6S)-4-(hydroxymethyl)-6-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}cyclohex-4-ene-1,2,3-triol

Other name(s): vldH (gene name)

Systematic name: validoxylamine-A 7'-phosphate phosphohydrolase

Comments: The enzyme, characterized from the bacterium Streptomyces hygroscopicus subsp. limoneus, is involved in the biosynthesis of the antifungal agent validamycin A.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Asamizu, S., Yang, J., Almabruk, K.H. and Mahmud, T. Pseudoglycosyltransferase catalyzes nonglycosidic C-N coupling in validamycin a biosynthesis. J. Am. Chem. Soc. 133 (2011) 12124-12135. [PMID: 21766819]

[EC created 2016]

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