IUBMB Enzyme Nomenclature

EC 3.1.3.29

Accepted name: N-acylneuraminate-9-phosphatase

Reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate

For diagram of reaction click here.

Other name(s): acylneuraminate 9-phosphatase; N-acylneuraminic acid 9-phosphate phosphatase; N-acylneuraminic (sialic) acid 9-phosphatase

Systematic name: N-acylneuraminate-9-phosphate phosphohydrolase

Comments: The enzyme, found in vertebrates, is equally active with N-acetylneuraminate 9-phosphate and N -glycoloylneuraminate 9-phosphate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37288-13-4

References:

1. Jourdian, G.W., Swanson, A.L., Watson, D., and Roseman S. Isolation of sialic acid 9-phosphatase from human erythrocytes. J. Biol. Chem. 239 (1964) PC2714–PC2716.[PMID: 14235556]

2. Jourdian, G.W., Swanson, A., Watson, D. and Roseman, S. N-Acetylneuraminic (sialic) acid 9-phosphatase. Methods Enzymol. 8 (1966) 205-208.

3. Maliekal, P., Vertommen, D., Delpierre, G. and Van Schaftingen, E. Identification of the sequence encoding N-acetylneuraminate-9-phosphate phosphatase. Glycobiology 16 (2006) 165–172. [PMID: 16237198]

[EC 3.1.3.29 created 1972]


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