IUBMB Enzyme Nomenclature


Accepted name: thymidylate 5'-phosphatase

Reaction: thymidylate + H2O = thymidine + phosphate

Other name(s): thymidylate 5'-nucleotidase; deoxythymidylate 5'-nucleotidase; thymidylate nucleotidase; deoxythymidylic 5'-nucleotidase; deoxythymidylate phosphohydrolase; dTMPase

Systematic name: thymidylate 5'-phosphohydrolase

Comments: Acts on 5-methyl-dCMP and on TMP, but more slowly than on dTMP.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9026-80-6


1. Aposhian, H.V. and Tremblay, G.Y. Deoxythymidylate 5'-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C. J. Biol. Chem. 241 (1966) 5095-5101. [PMID: 4958986]

[EC created 1972]

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