Reaction: thymidylate + H2O = thymidine + phosphate
Other name(s): thymidylate 5'-nucleotidase; deoxythymidylate 5'-nucleotidase; thymidylate nucleotidase; deoxythymidylic 5'-nucleotidase; deoxythymidylate phosphohydrolase; dTMPase
Systematic name: thymidylate 5'-phosphohydrolase
Comments: Acts on 5-methyl-dCMP and on TMP, but more slowly than on dTMP.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9026-80-6
1. Aposhian, H.V. and Tremblay, G.Y. Deoxythymidylate 5'-nucleotidase. Purification and properties of an enzyme found after infection of Bacillus subtilis with phage SP5C. J. Biol. Chem. 241 (1966) 5095-5101. [PMID: 4958986]