IUBMB Enzyme Nomenclature


Accepted name: streptomycin-6-phosphatase

Reaction: streptomycin 6-phosphate + H2O = streptomycin + phosphate

Other name(s): streptomycin 6-phosphate phosphatase; streptomycin 6-phosphate phosphohydrolase; streptomycin-6-P phosphohydrolase

Systematic name: streptomycin-6-phosphate phosphohydrolase

Comments: Also acts on dihydrostreptomycin 3'α,6-bisphosphate and streptidine 6-phosphate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9055-33-8


1. Walker, J.B. and Skorvaga, M. Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6-phosphate to inosamines, streptamine, and 2-deoxystreptamine. J. Biol. Chem. 248 (1973) 2441-2446. [PMID: 4121457]

2. Walker, M.S. and Walker, J.B. Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy-scyllo-inositol phosphate and streptomycin-(streptidino)phosphate. J. Biol. Chem. 246 (1971) 7034-7040. [PMID: 4331203]

[EC created 1976]

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