Reaction: 4-nitrophenyl phosphate + H2O = 4-nitrophenol + phosphate
Other name(s): nitrophenyl phosphatase; p-nitrophenylphosphatase; para-nitrophenyl phosphatase; K-pNPPase; NPPase; PNPPase; Ecto-p-nitrophenyl phosphatase; p-nitrophenylphosphate phosphohydrolase
Systematic name: 4-nitrophenylphosphate phosphohydrolase
Comments: A number of other substances, including phenyl phosphate, 4-nitrophenyl sulfate, acetyl phosphate and glycerol phosphate, are not substrates.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9073-68-1
References:
1. Attias, J. and Bonnet, J.L. A specific alkaline p-nitrophenylphosphatase activity from baker's yeast. Biochim. Biophys. Acta 268 (1972) 422-430. [PMID: 4554643]
2. Attias, J. and Durand, H. Further characterization of a specific p-nitrophenylphosphatase from baker's yeast. Biochim. Biophys. Acta 321 (1973) 561-568. [PMID: 4357666]