IUBMB Enzyme Nomenclature


Accepted name: [myosin-light-chain] phosphatase

Reaction: [myosin light-chain] phosphate + H2O = [myosin light-chain] + phosphate

Other name(s): myosin light chain kinase phosphatase; myosin phosphatase; myosin phosphatase; protein phosphatase 2A; myosin-light-chain-phosphatase

Systematic name: [myosin-light-chain]-phosphate phosphohydrolase

Comments: The enzyme is composed of three subunits. The holoenzyme dephosphorylates myosin light chains and EC, myosin-light-chain kinase, but not myosin; the catalytic subunit acts on all three substrates.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 60241-39-6


1. Pato, M.D. and Adelstein, R.S. Purification and characterization of a multisubunit phosphatase from turkey gizzard smooth muscle. The effect of calmodulin binding to myosin light chain kinase on dephosphorylation. J. Biol. Chem. 258 (1983) 7047-7054. [PMID: 6304072]

[EC created 1986]

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