IUBMB Enzyme Nomenclature


Accepted name: caldesmon-phosphatase

Reaction: caldesmon phosphate + H2O = caldesmon + phosphate

Other name(s): SMP-I; smooth muscle caldesmon phosphatase

Systematic name: caldesmon-phosphate phosphohydrolase

Comments: Dephosphorylation activates the calmodulin- and actin-binding ability of the protein caldesmon.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 93229-71-1


1. Ngai, P.K. and Walsh, M.P. Inhibition of smooth muscle actin-activated myosin Mg2+-ATPase activity by caldesmon. J. Biol. Chem. 259 (1984) 13656-13659. [PMID: 6150036]

[EC created 1989]

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