Reaction: caldesmon phosphate + H2O = caldesmon + phosphate
Other name(s): SMP-I; smooth muscle caldesmon phosphatase
Systematic name: caldesmon-phosphate phosphohydrolase
Comments: Dephosphorylation activates the calmodulin- and actin-binding ability of the protein caldesmon.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 93229-71-1
References:
1. Ngai, P.K. and Walsh, M.P. Inhibition of smooth muscle actin-activated myosin Mg2+-ATPase activity by caldesmon. J. Biol. Chem. 259 (1984) 13656-13659. [PMID: 6150036]