Reaction: myo-inositol hexakisphosphate + H2O = 1L-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate
Systematic name: myo-inositol-hexakisphosphate 5-phosphohydrolase
Comments: The enzyme attacks the product of the above reaction more slowly to yield Ins(1,2,3)P3.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 357208-41-4
References:
1. Barrientos, L., Scott, J.J. and Murthy, P.P. Specificity of hydrolysis of phytic acid by alkaline phytase from lily pollen. Plant Physiol. 106 (1994) 1489-1495. [PMID: 7846160]