IUBMB Enzyme Nomenclature


Accepted name: 5"-phosphoribostamycin phosphatase

Reaction: 5"-phosphoribostamycin + H2O = ribostamycin + phosphate

For diagram of reaction click here.

Other name(s): btrP (gene name); neoI (gene name)

Systematic name: 5"-phosphoribostamycin phosphohydrolase

Comments: Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. No metal is required for activity.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Kudo, F., Fujii, T., Kinoshita, S. and Eguchi, T. Unique O-ribosylation in the biosynthesis of butirosin. Bioorg. Med. Chem. 15 (2007) 4360-4368. [PMID: 17482823]

[EC created 2012]

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