IUBMB Enzyme Nomenclature


Accepted name: pseudouridine 5'-phosphatase

Reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate

Other name(s): pseudouridine 5'-monophosphatase; 5'-PsiMPase; HDHD1

Systematic name: pseudouridine 5'-phosphohydrolase

Comments: Requires Mg2+ for activity.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number:


1. Preumont, A., Rzem, R., Vertommen, D. and Van Schaftingen, E. HDHD1, which is often deleted in X-linked ichthyosis, encodes a pseudouridine-5'-phosphatase. Biochem. J. 431 (2010) 237-244. [PMID: 20722631]

[EC created 2014]

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