Reaction: Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate
Other name(s): glucurono-2-sulfatase
Systematic name: polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase
Comments: Does not act on iduronate 2-sulfate residues (cf. EC 3.1.6.13 iduronate-2-sulfatase)
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 98597-45-6
References:
1. Shaklee, P.N., Glaser, J.H. and Conrad, H.E. A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans. J. Biol. Chem. 260 (1985) 9146-9149. [PMID: 4019466]