IUBMB Enzyme Nomenclature


Accepted name: geranylgeranyl diphosphate diphosphatase

Reaction: geranylgeranyl diphosphate + H2O = geranylgeraniol + diphosphate

For diagram click here.

glossary: plaunotol = 18-hydroxygeranylgeraniol

Other name(s): geranylgeranyl diphosphate phosphatase

Systematic name: geranyl-diphosphate diphosphohydrolase

Comments: Involved in the biosynthesis of plaunotol. There are two isoenzymes with different ion requirements. Neither require Mg2+ but in addition PII is inhibited by Zn2+, Mn2+ and Co2+. It is not known which isoenzyme is involved in plaunotol biosynthesis.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Nualkaew, N., De-Eknamkul, W., Kutchan, T.M. and Zenk, M.H. Membrane-bound geranylgeranyl diphosphate phosphatases: purification and characterization from Croton stellatopilosus leaves. Phytochemistry 67 (2006) 1613-1620. [PMID: 16445953]

[EC created 2009]

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