IUBMB Enzyme Nomenclature


Accepted name: 3α(S)-strictosidine β-glucosidase

Reaction: strictosidine + H2O = D-glucose + strictosidine aglycone

For diagram click here.

Systematic name: strictosidine β-D-glucohydrolase

Comments: Does not act on a number of closely related glycosides. Strictosidine is a precursor of indole alkaloids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 73379-57-4


1. Hemscheidt, T. and Zenk, M.H. Glucosidases involved in indole alkaloid biosynthesis of Catharanthus cell cultures. FEBS Lett. 110 (1980) 187-191. [PMID: 6768587]

2. Barleben, L., Ma, X., Koepke, J., Peng, G., Michel, H. and Stöckigt, J. Expression, purification, crystallization and preliminary X-ray analysis of strictosidine glucosidase, an enzyme initiating biosynthetic pathways to a unique diversity of indole alkaloid skeletons. Biochim. Biophys. Acta 1747 (2005) 89-92. [PMID: 15680242]

[EC created 1984]

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