Reaction: Hydrolysis of (1→6)-linkages between α-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin
Other name(s): α-L-fucosidase; 1,6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase
Systematic name: 6-L-fucosyl-N-acetyl-D-glucosaminylglycopeptide fucohydrolase
Comments: The enzyme from Aspergillus niger does not act on 1,2-, 1,3-, or 1,4-L-fucosyl linkages.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 102925-35-9
References:
1. Yazawa, S., Madiyalakan, R., Chawda, R.P. and Matta, K.L. α-L-Fucosidase from Aspergillus niger: demonstration of a novel α-L-(1→6)-fucosidase acting on glycopeptides. Biochem. Biophys. Res. Commun. 136 (1986) 563-569. [PMID: 2423086]