IUBMB Enzyme Nomenclature

EC 3.2.1.50

Accepted name: α-N-acetylglucosaminidase

Reaction: Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-α-D-glucosaminides

Other name(s): α-acetylglucosaminidase; N-acetyl-α-D-glucosaminidase; N-acetyl-α-glucosaminidase; α-D-2-acetamido-2-deoxyglucosidase

Systematic name: α-N-acetyl-D-glucosaminide N-acetylglucosaminohydrolase

Comments: Hydrolyses UDP-N-acetylglucosamine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37288-40-7

References:

1. von Figura, K. Human α-N-acetylglucosaminidase. 1. Purification and properties. Eur. J. Biochem. 80 (1977) 523-533. [PMID: 411658]

2. von Figura, K. Human α-N-acetylglucosaminidase. 2. Activity towards natural substrates and multiple recognition forms. Eur. J. Biochem. 80 (1977) 535-542. [PMID: 923593]

3. Weissmann, B., Rowen, G., Marshall, J. and Friederici, D. Mammalian α-acetylglucosaminidase. Enzymic properties, tissue distribution, and intracellular localization. Biochemistry 6 (1967) 207-214. [PMID: 4291567]

4. Werries, E., Wollek, E., Gottschalk, A. and Buddecke, E. Separation of N-acetyl-α-glucosaminidase and N-acetyl-α-galactosaminidase from ox spleen. Cleavage of the O-glycosidic linkage between carbohydrate and polypeptide in ovine and bovine submaxillary glycoprotein by N-acetyl-α-galactosaminidase. Eur. J. Biochem. 10 (1969) 445-449. [PMID: 5348072]

[EC 3.2.1.50 created 1972]


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