IUBMB Enzyme Nomenclature


Accepted name: 1,2-α-L-fucosidase

Reaction: methyl-2-α-L-fucopyranosyl-β-D-galactoside + H2O = L-fucose + methyl β-D-galactoside

Other name(s): almond emulsin fucosidase; α-(1→2)-L-fucosidase

Systematic name: 2-α-L-fucopyranosyl-β-D-galactoside fucohydrolase

Comments: Highly specific for non-reducing terminal L-fucose residues linked to D-galactose residues by a 1,2-α-linkage. Not identical with EC 1,3-α-L-fucosidase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37288-45-2


1. Bahl, O.P. Glycosidases of Aspergillus niger. II. Purification and general properties of 1,2-α-L-fucosidase. J. Biol. Chem. 245 (1970) 299-304. [PMID: 5460888]

2. Ogata-Arakawa, M., Muramatsu, T. and Kobata, A. α-L-Fucosidases from almond emulsin: characterization of the two enzymes with different specificities. Arch. Biochem. Biophys. 181 (1977) 353-358. [PMID: 18111]

3. Reglero, A. and Cabezas, J.A. Glycosidases of molluscs. Purification and properties of α-L-fucosidase from Chamelea gallina L. Eur. J. Biochem. 66 (1976) 379-387. [PMID: 7458]

[EC created 1972]

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