IUBMB Enzyme Nomenclature

EC 3.4.21.65

Accepted name: thermomycolin

Reaction: Rather nonspecific hydrolysis of proteins. Preferential cleavage: Ala, Tyr, Phe in small molecule substrates

Other names: thermomycolase

Comments: A peptidase of family S8 (subtilisin family) from the thermophilic fungus Malbranchea pulchella var. sulfurea containing Cys, but not inhibited by p-mercuribenzoate. Very thermostable. Formerly included in EC 3.4.21.14

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 52233-31-5

References

1. Gaucher, G.M. and Stevenson, K.J. Thermomycolin. Methods Enzymol. 45 (1976) 415-433. [PMID: 1012007]

[EC 3.4.21.65 created 1992 (EC 3.4.21.14 created 1961 as EC 3.4.4.16, transferred 1972 to EC 3.4.21.14, modified 1986, part incorporated 1992)]

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