IUBMB Enzyme Nomenclature


Accepted name: actinidain

Reaction: Similar to that of papain

Other names: actinidin; Actinidia anionic protease; proteinase A2 of Actinidia chinensis

Comments: From the kiwi fruit or Chinese gooseberry (Actinidia chinensis). In peptidase family C1 (papain family)

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 39279-27-1


1. Baker, E.N., Boland, M.J., Calder, P.C. and Hardman, M.J. The specificity of actinidin and its relationship to the structure of the enzyme. Biochim. Biophys. Acta 616 (1980) 30-34. [PMID: 7002215]

2. Kamphuis, I G., Drenth, J. and Baker, E.N. Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain. J. Mol. Biol. 182 (1985) 317-329. [PMID: 3889350]

3. Baker, E.N. and Drenth, J. The thiol proteases: stucture and mechanism. In Biological Macromolecules and Assemblies. Vol. 3. Active Sites of Enzymes (Jurnak, F.A. and McPherson, A., eds), pp. 314-368 (1987) John Wiley and Sons, Inc., New York

[EC created 1978]

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