Reaction: Similar to that of papain
Other name(s): chymopapain A; chymopapain B; chymopapain S
Comments: The major endopeptidase of papaya (Carica papaya) latex. It has multiple chromatographic forms. In peptidase family C1 (papain family). Formerly EC 3.4.4.11
Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 9001-09-6
References:
1. Brocklehurst, K., Willenbrock, F. and Salih, E. Cysteine proteinases. In New Comprehensive Biochemistry Vol. 16, Hydrolytic Enzymes (Neuberger, A. and Brocklehurst, K., eds), pp. 39-158 (1987) Elsevier, Amsterdam
2. Jacquet, A., Kleinschmidt, T., Schnek, A.G., Looze, Y. and Braunitzer, G. The thiol proteinases from the latex of Carica papaya L. III. The primary structure of chymopapain. Biol. Chem. Hoppe-Seyler 370 (1989) 425-434. [PMID: 2500950]
3. Buttle, D.J., Dando, P.M., Coe, P.F., Sharp, S.L., Shepherd, S.T. and Barrett, A.J. The preparation of fully active chymopapain free of contaminating proteinases. Biol. Chem. Hoppe-Seyler 371 (1990) 1083-1088. [PMID: 2085414]