IUBMB Enzyme Nomenclature


Accepted name: polyporopepsin

Reaction: Milk clotting activity, broad specificity, but fails to cleave Leu15-Tyr or Tyr16-Leu of insulin B chain

Other names: Polyporus aspartic proteinase; Irpex lacteus aspartic proteinase; Irpex lacteus carboxyl proteinase B

Comments: From the basidiomycete Polyporus tulipiferae (formerly Irpex lacteus). In peptidase family A1 (pepsin A family)

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 61573-73-7


1. Kobayashi, H., Kusakabe, I. and Murakami, K. Substrate specificity of a carboxyl proteinase from Irpex lacteus. Agric. Biol. Chem. 47 (1983) 1921-1923

2. Kobayashi, H., Sekibata, S., Shibuya, H., Yoshida, S., Kusakabe, I. and Murakami, K. Cloning and sequence analysis of cDNA for Irpex lacteus aspartic proteinase. Agric. Biol. Chem. 53 (1989) 1927-1933

[EC created 1992]

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