IUBMB Enzyme Nomenclature

EC 3.4.24.49

Accepted name: bothropasin

Reaction: Cleavage of His⁵Leu, His¹⁰Leu, Ala¹⁴Leu, Tyr¹⁶Leu and Phe²⁴Phe in insulin B chain

Other name(s): Bothrops jararaca venom metalloproteinase

Comments: Caseinolytic endopeptidase of jararaca snake (Bothrops jararaca) venom; 48 kDa. In peptidase family M12

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 84788-89-6

References:

1. Mandelbaum, F.J., Reichel, A.P. and Assakura, M.T. Isolation and characterization of a proteolytic enzyme from the venom of the snake Bothrops jararaca (jararaca). Toxicon 20 (1982) 955-972. [PMID: 6819660]

[EC 3.4.24.49 created 1992]

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