Reaction: Cleavage of Asn3Gln, Gln4
His, His10
Leu, Ala14
Leu, and Tyr16
Leu in insulin B chain
Other names: Ophiophagus metalloendopeptidase
Comments: A 70 kDa endopeptidase from the venom of the king cobra (Ophiophagus hannah)
Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: ???
References:
1. Yamakawa, Y. and Omori-Satoh, T. A protease in the venom of king cobra (Ophiophagus hannah): purification, characterization and substrate specificity on oxidized insulin B-chain. Toxicon 26 (1988) 1145-1155. [PMID: 3070833]