Asp-. Acts very slowly on -XaaGlu
Reaction: Hydrolyses polypeptides on the amino-side of Asp in -XaaAsp-. Acts very slowly on -XaaGlu
Comments: A zinc metalloendopeptidase In peptidase family M12 (astacin family), secreted by the bacterium Flavobacterium meningosepticum . The specificity is similar to that of (EC 3.4.24.33), peptidyl-Asp metalloendopeptidase from Pseudomonas fragi but the two are reported to be structurally dissimilar
Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 167973-66-2
References
1. Tarentino, A.L., Quinones, G., Grimwood, B.G., Hauer, C.R. and Plummer, T.H., Jr. Molecular cloning and sequence analysis of flavastacin: an O-glycosylated prokaryotic zinc metalloendopeptidase.Arch. Biochem. Biophys. 319 (1995) 281-285. [PMID: 7771796]