Reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate
For diagram click here.
Other name(s): penicillin acylase; benzylpenicillin acylase; novozym 217; semacylase; α-acylamino-β-lactam acylhydrolase; ampicillin acylase
Systematic name: penicillin amidohydrolase
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9014-06-6
References:
1. Sakaguchi, K. and Murao, S. A preliminary report on a new enzyme, "penicillin-amidase". J. Agric. Chem. Soc. Jpn. 23 (1950) 411 only.