IUBMB Enzyme Nomenclature

EC 3.5.1.12

Accepted name: biotinidase

Reaction: biotin amide + H2O = biotin + NH3

Other name(s): amidohydrolase biotinidase

Systematic name: biotin-amide amidohydrolase

Comments: Also acts on biotin esters.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9025-15-4

References:

1. Knappe, J., Brümer, W. and Biederbick, K. Reinigung und Eigenschaften der Biotinidase aus Schweinenieren und Lactobacillus casei. Biochem. Z. 338 (1963) 599-613.

2. Thoma, R.W. and Peterson, W.H. The enzymatic degradation of soluble bound biotin. J. Biol. Chem. 210 (1954) 569-579.

[EC 3.5.1.12 created 1961]


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