IUBMB Enzyme Nomenclature


Accepted name: jasmonoyl-L-amino acid hydrolase

Reaction: a jasmonoyl-L-amino acid + H2O = jasmonate + an L-amino acid

Glossary: tuberonic acid = 12-hydroxyjasmonate = {(1R,2R)-2-[(2Z)-5-hydroxypent-2-enyl]-3-oxo-cyclopentyl}acetate
jasmonate = {(1R,2R)-3-oxo-2-[(2Z)-pent-2-enyl]cyclopentyl}acetate

Other name(s): IAR3 (gene name); ILL4 (gene name); ILL6 (gene name)

Systematic name: jasmonoyl-L amino acid amidohydrolase

Comments: This entry includes a family of enzymes that recyle jasmonoyl-amino acid conjugates back to jasmonates. The enzymes from Arabidopsis thaliana have been shown to also act on 12-hydroxyjasmonoyl-L-isoleucine, generating tuberonic acid.

BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Widemann, E., Miesch, L., Lugan, R., Holder, E., Heinrich, C., Aubert, Y., Miesch, M., Pinot, F. and Heitz, T. The amidohydrolases IAR3 and ILL6 contribute to jasmonoyl-isoleucine hormone turnover and generate 12-hydroxyjasmonic acid upon wounding in Arabidopsis leaves. J. Biol. Chem. 288 (2013) 31701-31714. [PMID: 24052260]

[EC created 2017]

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