IUBMB Enzyme Nomenclature


Accepted name: N5-(cytidine 5'-diphosphoramidyl)-L-glutamine hydrolase

Reaction: N5-(cytidine 5'-diphosphoramidyl)-L-glutamine + H2O = cytidine 5'-diphosphoramidate + L-glutamate

Other name(s): N5-(cytidine 5'-diphosphoramidyl)-L-glutamine deacylase

Systematic name: N5-(cytidine 5'-diphosphoramidyl)-L-glutamine amidohydrolase

Comments: The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Taylor, Z.W., Brown, H.A., Holden, H.M. and Raushel, F.M. Biosynthesis of nucleoside diphosphoramidates in Campylobacter jejuni. Biochemistry 56 (2017) 6079-6082. [PMID: 29023101]

[EC created 2018]

Return to EC 3.5.1 home page
Return to EC 3.5 home page
Return to EC 3 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page