IUBMB Enzyme Nomenclature


Accepted name: ω-amidase

Reaction: A monoamide of a dicarboxylate + H2O = a dicarboxylate + NH3

Other name(s):α-keto acid-ω-amidase

Systematic name: ω-amidodicarboxylate amidohydrolase

Comments: Acts on glutaramate, succinamate and their 2-oxo derivatives.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9025-19-8


1. Meister, A., Levintow, L., Greenfield, R.E. and Abendschein, P.A. Hydrolysis and transfer reactions catalyzed by ω-amidase preparations. J. Biol. Chem. 215 (1955) 441-460.

2. Meister, A., Radhakrishnan, A.N. and Buckley, S.D. Enzymatic synthesis of L-pipecolic acid and L-proline. J. Biol. Chem. 229 (1957) 789-800.

[EC created 1961]

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