Reaction: urea + H2O = CO2 + 2 NH3
Systematic name: urea amidohydrolase
Comments: A nickel protein.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9002-13-5
References:
1. Dixon, N.E., Gazzola, C., Blakeley, R.L. and Zerner, B. Metal ions in enzymes using ammonia or amides. Science 191 (1976) 1144-1150.
2. Sumner, J.B. Urease, in Sumner, J.B. and Myrbäck, K. (Eds.), The Enzymes, vol. 1, Academic Press, New York, 1951, pp. 873-892.
3. Varner, J.E. Urease, in Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd edn., vol. 4, Academic Press, New York, 1960, pp. 247-256.