IUBMB Enzyme Nomenclature


Accepted name: 4-acetamidobutyryl-CoA deacetylase

Reaction: 4-acetamidobutanoyl-CoA + H2O = acetate + 4-aminobutanoyl-CoA

Other name(s): aminobutyryl-CoA thiolesterase; deacetylase-thiolesterase

Systematic name: 4-acetamidobutanoyl-CoA amidohydrolase

Comments: The enzyme also hydrolyses 4-aminobutanoyl-CoA to aminobutanoate and coenzyme A.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Ohsugi, M., Khan, J., Hensley, C., Chew, S. and Barker, H.A. Metabolism of L-β-lysine by a Pseudomonas. Purification and properties of a deacetylase-thiolesterase utilizing 4-acetamidobutyryl CoA and related compounds. J. Biol. Chem. 256 (1981) 7642-7651. [PMID: 6788773]

[EC created 1984]

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