IUBMB Enzyme Nomenclature


Accepted name: N,N-dimethylformamidase

Reaction: N,N-dimethylformamide + H2O = dimethylamine + formate

Other name(s): dimethylformamidase; DMFase

Systematic name: N,N-dimethylformamide amidohydrolase

Comments: An iron protein. Also acts on N-ethylformamide and N-methyl-formamide and, more slowly, on N,N-diethylformamide, N,N-dimethylacetamide and unsubstituted acyl amides.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 104645-73-0


1. Schär, H.-P., Holzmann, W., Ramos Tombo, G.M. and Ghisalba, O. Purification and characterization of N,N-dimethylformamidase from Pseudomonas DMF 3/3. Eur. J. Biochem. 158 (1986) 469-475. [PMID: 3732281]

[EC created 1989]

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