IUBMB Enzyme Nomenclature


Accepted name: arylalkyl acylamidase

Reaction: N-acetylarylalkylamine + H2O = arylalkylamine + acetate

Other name(s): aralkyl acylamidase

Systematic name: N-acetylarylalkylamine amidohydrolase

Comments: identified in Pseudomonas putida. Strict specificity for N-acetyl arylalkylamines, including N-acetyl-2-phenylethylamine, N-acetyl-3-phenylpropylamine, N-acetyldopamine, N-acetyl-serotonin and melatonin. It also accepts arylalkyl acetates but not acetanilide derivatives, which are common substrates of (EC, aryl acylamidase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Shimizu, S., Ogawa, J., Chung, M.C.-M., Yamada, H. Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2. Eur. J. Biochem. 209 (1992) 375-382. [PMID: 1396711]

[EC created 1999]

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