IUBMB Enzyme Nomenclature


Accepted name: (S)-N-acetyl-1-phenylethylamine hydrolase

Reaction: N-acetylphenylethylamine + H2O = phenylethylamine + acetate

Other name: (S)-N-acetyl-1-phenylethylamine amidohydrolase

Systematic name: (S)-N-acetylphenylethylamine:H2O hydrolase

Comments: Inhibited by phenylmethanesulfonyl fluoride. Some related acetylated compounds are hydrolysed with variable enantiomeric selectivities.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 192230-94-7


1. Brunella, A., Graf, M., Kittelmann, M., Lauma, K. and Ghisalba, O. Production, purification, and characterization of a highly enantioselective (S)-N-acetyl-1-phenylethyl amidohydrolase from Rhodococcus. Appl. Microbiol. Biotechnol. 47 (1997) 515-520.

[EC created 2000, modified 2002]

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